Effect of Extracts of Miso Dregs on Several Cultured Biophylactic Cell Lines

Abstract

To study physiological functions of miso at cellular level, the effects of extracts of some miso dregs on the cultured biophylactic cell lines such as monocytic (U-937), macrophage-like (U-M), hybridoma (HB4C5) and T Cell-derived (MOLT-3) cell lines were examined. The dialyzates of 0.1 N NaOH extract of barley and rice miso dregs enhanced the nitroblue tetrazolium (NBT) reducing activity of U-937 monocyte and U-M macrophage-like cell lines. The dialyzates of 0.1 N NaOH extract of barley miso dregs enhanced the IgM production of human-human hybridoma cell line, HB4C5. It was also found that the dialyzates of 0.1 N NaOH extract of rice miso dregs activated the T-cell-derived Molt-3 cell line.