Comparison of the Efficacy of Cryoballoon Ablation for Paroxysmal and Persistent Atrial Fibrillation

抄録

Background: Similar clinical outcomes have been demonstrated following pulmonary vein (PV) isolation (I) by radiofrequency catheter and cryoballoon ablation (CBA) in patients with paroxysmal atrial fibrillation (PAF). However, no comparison of the clinical outcome in patients with PAF and persistent AF (PerAF) by CBA has been reported to date. The purpose of this study was to compare the efficacy of PVI in patients with PAF and PerAF. Methods: CBA based PVI using a second-generation 28-mm balloon was performed in 58 patients with PAF and 32 with PerAF. Follow-up (FU) was based on outpatient clinic visits at 1, 3, 6, and 12 months, which included Holter electrocardiograms and ambulatory event electrocardiograms. Results: The freedom from atrial tachyarrhythmia recurrences following a single cryoballoon ablation in patients with PAF and PerAF did not differ significantly between the PAF and PerAF patients over a relatively shorter follow-up period, as estimated by the Kaplan-Meir method. Conclusion: CB-based PVI had similar efficacy for both PAF and PerAF.