Okajimas Folia Anatomica Japonica
Online ISSN : 1881-1736
Print ISSN : 0030-154X
ISSN-L : 0030-154X
Nuclei of the human raphe
Masakazu SHIBATANoboru GOTOJun GOTONaoko NONAKA
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2012 年 89 巻 1 号 p. 15-22

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Along the raphe of the brain stem, a series of small neuronal groups can be observed in the medulla oblongata, the pons and the mesencephalon. The neurons located in and adjacent to the raphe are considered to produce mainly serotonin (5-HT). The groups of nuclei containing 5-HT were first reported in experimental animals in the early 1960s1). The presence of such nuclei, however, has not yet been brought to light in the human brainstem except the few atlases2, 3), although in several neuroanatomy textbooks4), extrapolated data are shown in the form of drawings as if they were the data from the human brain. The aim of this study is to present microscopic photos of such raphe nuclei made from serial sections of the human brainstem, and to clarify the differences between findings in human and textbook drawings from animal data.
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