Abstract
The effects of ovariectomy on the mouse anterior pituitary was examined.
Theta-cells progressively decreased in number and in the majority of the cases castrated for 10 days or more these cells were almost not encountered. No sign of degeneration in this cell type was found throuhout this experimental period.
Acidophiles showed a slight increase in number and acidophiles with the negative image of Golgi's apparatus and with basophilic filamentous substances at the cell periphery were found more frequently than in the normal control mice.
Although a slight increace in number of delta-cells was observed, most of them were poorly granulated and reacted feebly to PAS reagent when compared with the normal controls.