Abstract
Of the mitochondria in human hepatic cells obtained from various cases of diseases, the specific modified findings were as follows:
(1) On light optics, those which show a high stainability thick, long rod shaped or spindle shaped. They are observed in a comparatively large number in the cells in the perilobular area of the liver.
(2) On electron optics, those which show an extreme swelling some reaching 1.5μ to 4.0, μ in the long axis. They show an unclear limiting membrane and cristae. Some of them show a destruction of the limiting membrane, a defect of cristae, coagulation in the mitochondrial matrix, revealing various findings. Such findings are considered to correspond to those on light optics.
(3) In light and electron optics, the various modified findings of mitochondria seem to be subjected to a kind of degeneration.
(4) The various modified finding of mitochondria do not selectively appear in the materials obtained from various cases of diseases. Still, they seem to appear rather frequently in severe cases.
