Abstract
Distribution of histological changes in limb muscles of dystrophic mice varying in age from 3 to 16 weeks were observed. With the younger group, dystrophic changes in each muscle tended to be grouped in each muscle. In the advanced cases muscular involvement was not uniform, but there tended to be variation in the same muscular involvement. Muscle involvement was more severe in older dystrophic mice than in younger ones. It is likely that there tends to be more severe in the extensor and adductor muscles than in the flexor group muscles. It is also likely that there are no histological differences between the red and the white muscle, because both fasciculi, such as the soleus and gastrocnemius are already affected in 3-week-old dystrophic mice.
