脳と発達
Online ISSN : 1884-7668
Print ISSN : 0029-0831
ISSN-L : 0029-0831
Isonicotinic Acid Hydrazid (INAH) による精神神経障害の発生機序に関する研究
第4篇Alcohol添加がINAH痙攣に及ぼす影響について
伊藤 進
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ジャーナル フリー

1970 年 2 巻 3 号 p. 342-348

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Experimental studies using rats were con.- ducted to study the effects of alcohol administration on the occurrence of INAH-induced convulsions.
As a result of this experimental studies, it was observed that alcohol, when it was administered simultaneously with INAH, significantly repressed the occurrence of convulsions.
It might be considered that the large doses of acetoacetic acid producing as metabolite of alcohol minimizes the convulsive acting of IN AH, combining with it in a living body.
Then, it might be considered that the metabolic speed of alcohol was interfered by coexisting INAH in vivo.
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