Development of Skincare Formulation Having an α-Gel Structure Containing a Large Amount of Water

Abstract

Intercellular lipids of the stratum corneum play an important role in maintaining healthy skin. Forming lamellar structures of intercellular lipids parallel to the skinsurface contributes to water holding property and barrier function of the stratum corneum. The new skincare formulation technique, “α-gel containing a large amount of water” with pseudo-ceramide, has been developed for forming “intercellular lipids-like” lamellar film on skin.

The biomimetic formulation and the study of intercellular lipids are reviewed from a skin care cosmetic point of view.