2023 Volume 23 Issue 11 Pages 559-567
In recent years, much progress has been made in research on human resident bacterial flora owing to the development of analysis equipment such as next-generation sequencers and improvements in sample processing technology. The entire picture of resident microbiota is being clarified not only with respect to the types and proportions of bacteria that constitute the microbiota but also the crosstalk between bacteria. Resident bacterial flora are deeply involved in human health; therefore, disruption of their balance and loss of diversity (dysbiosis) can cause poor health and disease. In this paper, we first explain the characteristics of each microbiota that forms in the intestine, oral cavity, and skin and discuss recent advances. We then present information on skin care and disease therapy based on regulation of the resident flora in the skin.
