Special Topics from Japan Thrombotic and Hematostatic Reactions to Bathing in Very Hot Hot-Spring

抄録

  Very hot hot-spring is loved by the Japanese, although it might cause thrombotic events. It causes addiction to hyperthermia possibly because of an increase in the production of morphine-like substance. Increases in platelet activation, adhesion molecules on the platelet surface, platelet-derived microparticles, and blood viscosity as well as decreases in fibrinolytic capacity and blood pressure were observed after bathing in very hot hot-spring. Bathing in very hot hot-spring is not recommended for the elderly in view of age-related changes in endothelial function, fibrinolytic capacity, dehydration, and dysregulation of blood pressure. Instead, hydrotherapy or bathing in hot-spring in temperatures under 42°C is beneficial with little risk regarding hemostasis and thrombosis.