Pseudomonas fluorescens菌体成分 (T. T. G.) による小児副鼻腔炎の治療経験
1958 年 1 巻 1 号 p. 75-79,100
詳細
1958 年 1 巻 1 号 p. 75-79,100
T. T. G. is a substance extracted from Pseudomonas fluorescens, a non-pathogenic microorganism found in the earth earth.It has a ACTH-like action but, unlike ACTH or cortisone, there is no danger of it causing degenerative changes in the respective endocrine glands with continuous use.It is believed, rather, that it acts in the form of a suitable stressor which plays a part in improving the constitution impaired by dysfunction of the endocrine system.
This action of T. T. G. has prompt us to give this substance a trial in the treatment of chronic sinusitis in children. After thorough clinical examinations, 35 patients were selecteds fo this study. T. T. G. in tablet from, one tablet daily, was given for over 5 weeks to each of these patients and the clinical effects were minutely observed.
The treatments were very effective in 4 cases, effective in 27 and ineffective in 4 as recurrences occurred, showing an overall effective rate of 89%. The good therapeutic results obtained were more than we had anticipated.
From the point of view of its mode of action, there is rationality in its therapeutic effects and, moreover, as it is suitable for prolonged continuous use, we believe T T G offers new significance in the treatment of a sinusitis.
