耳鼻咽喉科展望
Online ISSN : 1883-6429
Print ISSN : 0386-9687
ISSN-L : 0386-9687
鼻副鼻腔形質細胞腫症例
興味ある治療経過について
前坂 明男梅田 良三豊田 文一
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ジャーナル フリー

1972 年 15 巻 5 号 p. 665-669,582

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A 15-year-old girl was admitted on April 16, 1969 with the complaint of a reddish peasized tumor in the right nasal cavity. A biopsy of the tumor showed extramedullary plasmacytoma. Bence-Jones test was negative, and there were no abnormalities in the X-ray findings of the cranium or skeleton. Only a low albumin/globulin ratio was observed.
Betatron irradiation treatment was performed through the right lateral surface of the nose, and after 4, 000 rad. irradiation the tumor disappeared completely. She was discharged after a 65-day-admission.
On March 23, 1970, she had a new reddish tumor in the left middle nasal meatus, Bilateral paranasal sinusitis was also observed. The patient was again admitted on April 8, 1970. Plasmacytomas were found in both nasal cavities and both maxillary sinuses after histopathological examinations of specimens. This time, no effect was observed on the tumor with betatron or telecobalt irradiation treatment.
Corticosteroid treatment was adopted. Betamethason (Rinderon: Shionogi) was given 5 mg daily for 17 days, the tumors started decreasing in size. Corticosteroid was lessened gradually, and on August 24, 1970, the tumor disappeared both in inspection and by histopathological examination.
She was discharged on December 14, 1970 after 250 days, She has had no recurrence of the tumor for 19 months.
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