1972 年 15 巻 6 号 p. 759-764,728
Intravenous and nasal olfactory tests were performed on 107 cases with disturbance of olfactory sense using Alinamin (Thiamin propyl sulfid). Of 83 cases with peripheral disturbance, 56 cases were hyposmic and the remaining 28 were anosmic. Of 24 cases with central disturbance, 6 were hyposmic and 18 were anosmic.
Complete loss of olfactory sense in which no responce was obtained even by the intravenous test was seen in 10 out of 83 cases of peripheral disturbance (12%), and in 14 of 24 cases with central disturbance (58%).
Olfactory test in cases with chronic sinusitis showed positive or negative results depending upon the degree of pathological changes of the olfactory mucosa. Loss of olfactory sense due to morphological changes of the intranasal structures is presumed to be rare.