嗄声を主訴とした原発性肺癌の1剖検例

抄録

Otorhinolaryngologists and bronchoesophagologists often encounter patients whose chief complaint is hoarseness. Although hoarsseness is complained chiefly in only about 2.6 per cent of all cases of lung cancer, its possible association with lung cancer should be kept is mind and such cases should be carefully examined, as illustrated by the following case.
The patient, a 57-year-old man, complaining chiefly of hoarseness, was found to have progressive paralysis of the left and then right vocal cords. Chest films disclosed abnormal shadows in the right upper and middle lobes. Subsequent bronchoscopic examinations, chest angiograms and bronchograms established the diagnosis of primary lung cancer, stage III, which was treated with anti-tumor drugs but the patient expired 5 months later.
Autopsy revealed wide-spread metastatic involvement, to regional lymphnodes and distant organs. The clinical course and pathological findings are described in detail and the hoarseness was probably due to metastasis to the peribronchial and cervical lymphnodes with cancerous invasion into the peripheral nerve tissue.