抄録
We used a combined chemotherapy with CDDP and 5-FU as a induction chemotherapy for various head and neck cancers since Jan. 1967. Ten cases were statiscally evaluated so far, in which 3 tongue cancer, 2 nasophraynx cancer, 2 ear cancer, 1 ethmoid cancer, 1 hypopharynx cancer and 1 larynx cancer were included.
The therapeutic result showed 100% response rate to the therapy eventualy with 4 cases of CR and 6 cases of PR. There were a decreare in the numbers of leucocyte, and paltelet. Nausea, vomitting and stomatitis frequenthy accompanied by this use. Despite these side effects, it was all posible to conclude the combined chemotherapy to be a good treatment of choice for head and neck cancer except one case.
