Using guinea pigs of ca. 250gr., the endolymphatic oxygen tension was measured by the polarographic principle.
The experiment was performed by inserting oxygen sensitive Pt microelectrodes into the scala media via stria vascularis.
The endolymphatic oxygen tension was 45.79±3.26 mmHg (means±SD) in 17 animals.
It decreased after asphyxia for one minute, increased after recovery of breathing, and recovered to the original level after overshooting.
In animals treated with Furosemide 60mg/kg via the femoral vein, the endolymphatic oxygen tension showed increase for ca. 10 minutes.
Ep and blood pressure were also measured and discussed.
