From standpoint of the inner ear circulation, we discussed the inner ear function. The subjects for this investigation included many guinea pigs and we gave them many kinds of hypotensive and vasopressor drugs. And so, we measured the blood pressure, EP and oxygen tension in the inner ear. The fluctuation of EP is too little change as compared with oxygen tension and blood pressure fluctuation. We fluctuated the blood pressure, for example by the intravenous injection of Trimetaphan camsilate, Adrenalin and the like. After injection, we found the facts of interesting tendency to return for the first level after it indicated increase or decrease tendency in a certain degree. Of course, these situation of change had great influence on volume of drugs. In these standpoint, in relation of experimental data for autonomic nervous system, we can consider existence of factors that regulate the inner ear function.