耳硬化症患者血清中の抗II型コラーゲン抗体価
1986 年 17 巻 1 号 p. 117-120
詳細
1986 年 17 巻 1 号 p. 117-120
In 18 cases of otosclerosis and 42 cases of chronic otitis media, anti-collagen antibody levels were determined by ELISA method. As the antigens, types I, II and III collagens separated and purified from human skin, articular cartilage and placenta were used. The secondary antibody used was goat anti-human IgG antibody. In sera from 4 cases of otosclerosis anti-type II collagen antibody of IgG class was detected. On the other hand, no such antibody was detected in sera of patients with chronic otitis media. In none of the cases anti-type I and type III collagen antibodies were detected.
