Ear Research Japan
Online ISSN : 1884-5797
Print ISSN : 0288-9781
ISSN-L : 0288-9781
実験的滲出性中耳炎におけるカルボシステインの効果
堀 文彦川内 秀之鈴木 正志茂木 五郎
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ジャーナル フリー

1988 年 19 巻 1 号 p. 297-299

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Although several pharmaceutical investigations have been attemped to eradicate middle ear effusion (MEE), there has been no conservative therapy fully effective, convenient, and safe for this disorder. Disturbance of the mucociliary transport system and release of proteolytic enzymes in the tympanic cavity and eustachian tube are probably the major pathogenesis of OME. This study was designed to investigate the therpeutic efficacy of Scarboxymethylcysteine (S-CMC), which restores lesion of the mucociliary clearance in experimental OME.
Results of this study showed the efficacy of S-CMC to protect and restore the mucociliary transport system in the middle ear against experimental OME.
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© 日本耳科学会
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