抄録
Bacterial antigens of Str. pneumoniae and Str. mitis in middle ear effusions (MEEs) were measured by ELISA using specific antisera. Antigen levels were compared with cytological findings and global appearances of MEEs. The antigen levels of Str. mitis were found to be related with the cytological finding of MEEs. Antigen levels in few cell type- and in neutrophil dominant type-MEE were lower than those in other types. The antigen levels of Str. pneumoniae in purulent type- and mucopurulent type-MEE were highter than those in mucinous type- and bloody type-MEE. The results suggest that the relation of various bacterial antigens in the MEEs, possibly derived from the nasopharynx, may stimulate the middle ear mucosa and may be one of causes for the chronicity of otitis media with effusion.
