抄録
In OME in children, the amounts of total and specific IgG antibodies against H. influenzae (nontypable) were investigated middle ear effusions (MEEs) in comparison with sera by laser nephelometry and ELISA. The amounts of IgG in MEEs were higher than those in sera. The MEEs/sera ratios of specific IgG antibodies in serous- and mucoid-groups were higher than that in glue-group. These data show that the bacterial infection and subsequent immune response contribute the prolongation of OME in serous-, mucoid-groups, while other factors add to them in glue-group.
