We have reported the presence of surfactant-like material in the middle ear mucosa and also suggested its possible role in the pathogenesis of otitis media with effusion. This study was designed to evaluate the efficacy of Surfacten to experimental otitis media, which was induced by injecting nonviable nontypable H. Influenzae. Our results suggested that Surfacten might have some therapeutic efficacy to otitis media with effusion.
