内リンパ管閉塞モルモットの内耳に対する硫酸ストレプトマイシン全身投与の影響
1989 年 20 巻 1 号 p. 79-80
詳細
1989 年 20 巻 1 号 p. 79-80
The effect of streptomycin sulfate (SM) on the sensory epithelia of the inner ear of guinea pigs were studied morphologically by light microscpoe and electron microscope. The guinea pigs, in which the right endolymphatic duct were oblierated surgically, were parenterally treated with SM 250mg/kg 15 times in one month.
The study revealed that SM caused more remarkable damage on the vestibular sensory cells of the operated side compared with that of the opposite. Degenerations of the vestibular endoorgans were (1) loss of sensory hairs of the cristae ampullares and maculae, (2) flattening of cristae ampullares. Those were the most remarkable in the lateral ampulla. The organ of Corti remained intact on both sides.
