抄録
KOS strain of HSV type I was instilled in the right middle ear cavity of normal rats. After inoculation, the vestibular ganglions were resected and submitted to histopathological and immunohistochemical investigations on the day in the experimental time schedule. The specimen of the 3, 4, 5th day after inoculation showed inflammatory changes in the vestibular ganglion on the side of inoculation. By immunofluorecent antibody staining, HSV antigens were proved in both sides in the specimen of the 1st and 5th day after inoculation, but in the 8th day, HSV antigens were not detected.