抄録
The bacterial adhesion to the mucosal surface is an initial event in the infection process. We investigated adhesin receptors of Streptococcus pneumoniae type 19 in the middle ear mucosa by the method reported by Nowicki et al. S pneumoniae were found to attach to epithelial cells of the middle ear mucosa and to accinal cells of the gland in the eusthacian tube. The pneumococcal attachment to the middle ear mucosa was inhibited by N-acetyl-D-glucosamine. The presence of pneumococcal adhesin receptors in the mucosal tissues, not only on the epithelial surfaces, suggests the bacterial stay in the tissue and it may cause the prolongation of the infection.