Ear Research Japan
Online ISSN : 1884-5797
Print ISSN : 0288-9781
ISSN-L : 0288-9781
中耳粘膜における肺炎球菌定着因子に対する受容体
吉村 弘之, 渡辺 徳武, 分藤 準一, 篠田 三徳, 茂木 五郎
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ジャーナル フリー

1990 年 21 巻 1 号 p. 51-52

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The bacterial adhesion to the mucosal surface is an initial event in the infection process. We investigated adhesin receptors of Streptococcus pneumoniae type 19 in the middle ear mucosa by the method reported by Nowicki et al. S pneumoniae were found to attach to epithelial cells of the middle ear mucosa and to accinal cells of the gland in the eusthacian tube. The pneumococcal attachment to the middle ear mucosa was inhibited by N-acetyl-D-glucosamine. The presence of pneumococcal adhesin receptors in the mucosal tissues, not only on the epithelial surfaces, suggests the bacterial stay in the tissue and it may cause the prolongation of the infection.
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© 日本耳科学会
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