Active Mechanismの現在
支持細胞の関与
2000 年 10 巻 2 号 p. 83-88
詳細
2000 年 10 巻 2 号 p. 83-88
The supporting cells of the organ of Corti are divided into 2 cell groups. One group consists of Deiters cells and Pillar cells which have a cytoskeleton within the cell body. Other group consists of the cells that are located to the outside in the organ of Corti, such as Hensen cell and do not have the cytoskeleton. All of the supporting cells are getting involved in the maintenance action of the environment of corti lymph around the hair cell by the recycling of K+. It is thought that Hensen cell is getting involved in the regulation of the endolymphtic potential and ion organization of the endolymph. On the other hand, Deiters cell has a possibility that it inhibitedly controlled of the outer hair cell-Deiters cell vibration complex by changing the flexibility of the cell long axis accompanied with intnacellular Ca2+incnease. However, Pmar cell does not admit such a mechanical adjustment action. It is suggested that extracellular ATP regulates the intracellular Ca2+level by the Ca mobilization from intracellular Ca2+store within the Deiters cell.
