A 60-year-old male suffered from left temporalgia and developed mastoiditis. A jugular foramen syndrome (cranial nerve IX, X and XII deficit) that occurred in spite of mastoidectomy was improved by means of dissection of petrosal part.
One month later. at the contra-lateral side of the jugular foramen syndrome, Gradenigo syndrome originated from mastoiditis occurred. Mastoidectomy resulted in improvement of clinical symptoms.
Five months after the surgery, the patient developed left superior orbital fissure syndrome (cranial nerve II, III and V palsy) with thickening of the dura mater which was demonstrated by Gd-DTPA MRI.
Corticosteroid therapy was effective except for blindness.
These clinical findings of cranial nerve palsies were suspected to be associated with the migrating disseminated multiple cranial neuropathy.
