抄録
In point-to-point reaching finger movement, blain plans movement trajectory prior to the movement. The brain has to change the motor planning in unexpected occurrence interfering with the on-going movement. The motor command generated in the primary motor cortex (Ml) can be modulated with the transcranial magnetic stimulation (TMS) in the voluntary movement. In the present study, we investigated the nature of the reaching finger movement after the stop-signal accompanied with the TMS of MI at the stop signal in order to elucidate the temporal function of MI for the inhibitory control of the voluntary finger movement. The finger stopped on the way to the target with stop signal delay (SSD) less than 250 ms in the task without TMS, whereas the finger reached close to the target even with the stop signal delay (SSD) less than 250 ms in the task with TMS. These results indicate that the TMS of the Ml disturbs the inhibitory motor control in the pre-programmed voluntary movement.