Solubility and Mechanical Strength of Beta-Tricalcium Phosphate Doped with Monovalent and Divalent Metal Ions

抄録

Beta-tricalcium phosphate (β-TCP) is an attractive bioactive material because of its high biological compatibility with living hard tissues and the formation of bonding to natural bone. However, the dissolution speed of β-TCP is relatively high in living body and mechanical strength of β-TCP is lower than natural bone. In order to overcome these disadvantages, we have investigated the solid solution of the metal ion into β-TCP. It could be found that β-TCP doped with metal ions inhibited β-α transformation at high temperature and the solubility of β-TCP powder doped with metal ions was lower than that of β-TCP without the addition of metal ions under in vitro condition. In this study, β-TCP powders doped with monovalent and divalent metal ions were prepared in consideration of the solid solution of metal ions into vacancy and calcium sites in the β-TCP structure, and solubility and mechanical properties of β-TCP were investigated.