抄録
Protein-losing enteropathy is relatively rare in Japan. Here we report on a case of protein-losing enteropathy associated with malignant lymphoma.
A male aged over 50 years visited our hospital because of body weight loss and edema on the lower extremities. The serum albumin level was less than 2.0 g/dl, but no abnormality was found in the urinalysis. Capsule endoscopy and single-balloon enteroscopy showed multiple mucosal injury located at the small intestine, and the pathological examination of the ulcer proved dilatation of the lymphatic vessels. The 99m-Tc sintigraphy revealed protein losing from the small intestine. The lymph nodes at the cervical region became enlarged at the same time, and the diagnosis of peripheral-type T cell lymphoma was made by biopsied specimen. After the patient underwent standard chemotherapy with cyclophosphamide, vincristine, doxorubicin, and prednisolone, protein loss from the intestine decreased as well as improvement of leg edema.