Examination of the diagnostic performance and histological grade of gastrointestinal stromal tumor by biopsy using techniques of endoscopic submucosal dissection

Abstract

The disease that becomes an operation adjustment such as gastrointestinal stromal tumor (GIST) is included in the submucosal tumor of the stomach. If there is no malignant opinion for small submucosal tumor, we often do the passage observation because the diagnosis is difficult. We diagnose the submucosal tumor of stomach by histologic examination using techniques of endoscopic submucosal dissection. We performed a biopsy using techniques of endoscopic submucosal dissection for gastric SMT less than 5cm in size in our hospital. For three cases being diagnosed with GIST and resected surgically we compared the biopsy specimen and the resected specimen for histological and examined the diagnostic performance and histological grade. As a result histological diagnosis of the biopsy specimen was the same in the resected specimen and histological grade with Ki-67 index was same result. In a few cases in the study histologic examination using techniques of endoscopic submucosal dissection is useful in the diagnosis of GIST and possible to predict histological grade before surgery.