Comparison of endoscopy and magnetic resonance enterocolonography in intestinal lesion of patients with Crohn's disease

Abstract

We use MR enterocolonography (MREC) to assess the activity of Crohn's disease (CD) in order to reduce patient's invasiveness. MREC is one method for investigating mucosal condition, and has spread in Europe and the United States in recent years because MREC has the advantages in the point that 1) no radiation exposure, 2) identifying the exact location, and 3) objective comparison between different time point. There are many reports of its high accuracy, thus MREC will spread widely in Japan from now on. Deep mucosal lesions are well detected by MREC from the former reports. We investigated whether MREC could detect less deep lesions in CD patients and its mismatch who received ileocolonoscopy and MREC at the same period. The detection rate by each of MREC finding for endoscopical findings of erosion or redness was not high, but detection rate for erosion became high if we admitted positive when at least one of MREC finding was observed. However, the finding of relative contrast enhancement in MREC admitted comparatively high false positive rate especially in superficial lesions.