Abstract
Endoscopic mucosal healing is a recent treatment goal for patients with Crohn's disease (CD) . Currently, cross-sectional imaging in the form of computed tomography/magnetic resonance (CT/MR) enterography (CTE/MRE) is an important tool for simultaneously assessing intestinal and extra-intestinal lesions of Crohn's disease. We assessed predictions related to relapse and the risk of surgery based on CTE findings in CD patients, comparing the simple endoscopic score for Crohn's disease (SES-CD) obtained by balloon enteroscopy (BE) with the novel CTE score. We found a strong relationship between SES-CD using BE and CTE scores. From SES-CD, it was possible to measure the proportion of remissions and surgery-free rates. From CTE scores, we also evaluated clinical outcomes in patients with CD of the proportion in remission. In patient groups assessed with active anal lesions, fistulas, bleeding, and abscesses according to CTE, a higher rate of surgery was evident compared to a group without these findings, similar to predictions based on BE. CTE is comparable to BE for predicting relapse and the risk of surgery in Crohn’s disease.
