Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been widely utilized for diagnosis of upper gastrointestinal pathologies. However, there is only a few reports for usage of such technique for biopsy of mediastinal lesions. In this article, we report the feasibility and safety of EUS-FNA for mediastinal lesions. From 2013 to 2016, a total of 198 EUS-FNA cases were performed in our institution. Among them, a total of 10 mediastinal lesions were performed. Outcome data was evaluated retrospectively. In these cases, the final diagnoses were, a case of lung cancer, breast cancer, cancer from unknown origin, malignant lymphoma, suspected lymphoma, sarcoidosis and schwannoma each. Three cases were of inflammatory adenopathies. There was no complication noted in all cases. In conclusion, EUS-FNA has a high accuracy, safe, and is minimally invasive for diagnosis of mediastinal lesions.
