A 60-year-old man with HCV liver cirrhosis was pointed out an early gastric cancer. EGD showed a 20 mm reddish slightly depressed lesion (Paris type 0-IIa) in the anterior wall of lower gastric body. Biopsy revealed well differentiated adenocarcinoma. The lesion was resected in a single piece by ESD. We closed the mucosal defect with clip with string technique and filling the dead space with fibrin glue to prevent complications. Second look endoscopy revealed wound remained closed POD 2. The mucosal defect completely healed 3 months after. We report successful closure of mucosal defect with endoloop/clips technique and filling fibrin glue for a high-risk patient.
