A 50-year-old male was admitted to our hospital due to small bowel obstruction. Contrast enhanced abdominal CT scan showed ileo-colic intussusception. The patient underwent colonoscopy which revealed an incarcerated ileal mass protruding through the ileocecal valve into the ascending colon. Attempted endoscopic reduction of the intussusception was unsuccessful, therefore, we inserted a transnasal ileus tube for decompression. The histopathological result of the biopsy sample was benign ulcerative lesion, Group1, however, laboratory investigation showed elevated serum IL-2 receptor level of 1634 U/ml and normal CEA, CA19-9 levels. Under the preoperative diagnosis of intussusception secondary to intestinal malignant lymphoma, ileocecal resection was performed. The histopathology of the resected specimen proved to be diffuse large B-cell lymphoma of the ileum. Since the malignant lymphoma of this case was staged as StageI disease, the patient was followed up without adjuvant chemotherapy. Up to now, the patient remains free of recurrence or metastasis under surveillance with serum IL-2 receptor level and contrast enhanced abdominal CT scans.
