A 31-year-old male had been receiving outpatient treatment for Crohn's disease of the small and large intestines for seven months. The patient presented to our hospital with body weight loss, slight fever and bleary eyes. Laboratory testing showed that the patient had fungal endophthalmitis and infective endocarditis by Candida parapsilosis. The patient was admitted to our hospital. Since cardiac ultrasonography showed verrucas on the aortic valve, aortic valve replacement was performed. An antimycotic was administered for fungal endophthalmitis. Treating this patient was extremely difficult since he concomitantly presented with fungal endophthalmitis and infective endocarditis caused by Candida parapsilosis.
In the medical treatment of Crohn's disease, it should be noted that patients may be at risk for complicated infections due to central venous catheter placement as well as administration of steroids, immunomodulatory agents, and biologics. If the patient's clinical condition deteriorates, infection should be suspected.
