The patient was a male in his 70s. Endoscopic submucosal dissection (ESD) was performed for early-stage gastric cancer in the anterior wall of the antral zone and gastric adenoma in the anterior wall of the lower gastric body. Subsequently, an elevated lesion appeared in the area of the ESD scar on the anterior wall of the antral zone. It grew to become a giant polyp of 40×30×23 mm in size 2.5 years after ESD of gastric cancer. Biopsy results showed hyperplastic polyps. However, ESD was performed because malignancy could not be ruled out due to its size, and progressive anemia. We describe a case in which a large gastric hyperplastic polyp was found in the ESD scar and was resected.
