Progress of Digestive Endoscopy(1972)
Online ISSN : 2189-0021
Print ISSN : 0389-9403
Case report
A Case of Gastrointestinal Amyloidosis Secondary to Rheumatoid Arthritis that Clinically Responded to Steroid and Dimethyl Sulfoxide Therapy
Makoto NakanoAtsushi MurataShuntaro YoshidaHiroaki NakayaShigeru AokiMasahiro FuchigamiShouhei TanakaNorimichi Nemoto
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JOURNAL FREE ACCESS

1993 Volume 43 Pages 200-203

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Abstract
The patient was a 56-year-old female with the chief complaint of watery diarrhea and abdominal pain. She had undergone right thoracoplasty due to pulmonary tuberculosis at the age of 19 and had been treated for rheumatoid arthritis from the time she was 48 years old.●改行● She showed apparent hypoproteinemia with total protein of 4.4g/dl and albumin of 2.2g/dl on admission. The condition was improved by either antidiarrheal drugs or intravenous hyperalimentation (IVH) and her general status worsened. Biopsy of both the rectal and gastric mucosa due to suspected gastrointestinal amyloidosis revealed amyloid deposition.●改行● Treatment with prednisolone at a daily dosage of 60mg was initiated, and as this was being tapered, oral dimethyl sulfoxide (DMSO) at a daily dosage of 4ml was instituted. The hypoproteinemia improved gradually and the diarrhea disappeared. The patient has been followed-up at our clinic without recurrence of symptoms.
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© 1993 Japan Gastroenterological Endoscopy Society Kanto Chapter
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