We Experienced Two Cases of Endoscopically Excised Neurogenic Colon Tumor

Abstract

Case 1 : A 41-year-old male. A polyp was discovered in large bowel X-rays conducted for the chief complaint of hemorrhage after defecation. A long, slender and elevated lesion (8mm) was discovered on the left of the transverse colon. Endoscopic polypectomy was conducted. In histological examination, spindle-shaped cells with clear cell body showed linear or curved trabecular alignment and were stained with S-100 protein and NSE but not with vimentin. The diagnosis of neurinoma was made.
Case 2 : A 56-year-old female. Large bowel endoscopy was carried out upon onset of melena during ambulatory treatment for idiopathic thrombocytopenic purpura and hypertension. The diagnosis of ischemic colitis was made. Although ischemic change were relieved in the re-examination conducted 40 days later, an elevated lesion of 6mm was discovered in the sigmoid colon. Endoscopic polypectomy was carried out. In histological examination, fascicular hypertrophy and ganglion cells were observed, with cells being stained with S-100 protein and NSE but not with vimentin. The diagnosis of neuroganglioma was made based on these findings.
These cases are reported with some reference to the literature because of endoscopic excision of neurogenic tumors with primary lesions in the large bowel is rare.