抄録
This study was made on the changes of the two-wall osseous defect and the depth of the inflabony pocket induced with lower first molar teeth of the adult dog. In addition to this, changes of lysosomal enzyme activity in pocket exudate and gingival tissue on diurnal reparation of the inflabony pocket were observed.
The results obtained were as follows:
1) Inflabony pocket was recovered to about 4mm depth in 3 weeks after operation.
2) In about 3 weeks the surface texture of gingiva turned to preoperative status.
3) The gingiva showed a tendency of a slight recession with the healing of inflamation.
4) From the X-ray finding clearly new bone formation was observed at root apex in 2 weeks after operation and appreciable reparation in 3 weeks.
5) In inflabony pocket exudate, N-acetyl-β-glucosaminidase and β-galactosidase showed highest activity on the seventh day but β-glucosidase was highest on the third day, acid phosphatase and alkaline phosphatase were highest on the fifth, and β-glucuronidase had little difference in activity between the third and fifth days with a slight decrease on the seventh day.
6) In gingiva, acid phosphatase, β-galactosidase, β-glucuronidase and alkalin phosphatase showed a highest activity on the fifth, and β-glucosidase had no difference in activity between the third and fifth days with a decrease on the seventh day. And N-acetyl-β-glucosaminidase showed higherr values on the fifth and seventh days than on the third.
From the above it was made clear that the activity of lysosomal enzyme in the inflabony pockets exudate and the gingival tissue became higher diurnally from the fifth to the seventh day with the healing of inflammation. Especially acid phosphatase was remarkably increased in activity on the fifth day.
