2015 Volume 28 Issue 5 Pages 711-713
The surface of NaYF4 NPs were successfully modified via stepwise modification procedure, ligand exchange and electrostatic adsorption reactions. The obtained PEGylated NaYF4 NPs showed high dispersion stability under physiological conditions. Furthermore, the PEGylated NaYF4 NPs displayed minimal cell cytotoxicity in the range of general criteria of RED-CNPs concentration for live cell imaging. Therefore, the obtained PEGylated NaYF4 NPs is a promising candidate of NIR imaging probes.