2020 Volume 33 Issue 3 Pages 333-336
We fabricated the pH-responsible polymer nano-film possessing carbamate groups, which were easily decomposed in acidic condition, in the linker moieties. In pH 7.4 phosphate buffer saline the number average diameter of pH-responsible polymer nano-film was about 350 nm and its size distribution had almost unchanged for 3 days. In pH 5.0 acetate buffer solution the scattering intensity of polymer nano-film in DLS measurement gradually decreased and it was difficult to measure the particle diameter of polymer nano-film after 15 h due to the lower scattering intensity. It was suggested that most of the polymer nano-film might be decomposed until 15 h.