The specific binding of 131I-rLH to slices of intrasplenic ovarian grafts (heterogeneous ovarian tumors) was less than that to slices of luteinized young rat ovaries or of intact normal adult ovaries. Uptake by slices of luteinized old rat ovaries of comparable age was also greater than that by the intrasplenic ovarian grafts, although the grafts accumulated significantly larger amounts of rLH than did liver, kidney or muscles (diaphragm).
