Lower Incidence of Nodular Hyperplasia of the Adrenal Cortex after Ovariectomy in Neonatally Estrogenized Mice than in the Controls

Abstract

Incidence of hyperplastic adrenocortical nodules was smaller in neonatally estrogenized mice than in the controls after ovariectomy performed at 40 days of age. The difference may be accounted for by lower serum levels of LH and FSH in the neonatally estrogenized, ovariectomized mice than in the ovariectomized controls.