Clinical and Histo-Pathological Studies on Congenital Biliary Atresia

-Part II The Nuclear DNA Measurements of Liver Cells and the Histochemical Studies-

Abstract

The histopathological studies on 84 resected livers taken at radical operations of congenital biliary atresia concluded that conditions of liver cell were devided into 3 groups (Cn classification) according to nuclei number of liver cells in (130μ) ²; i.e. C₁ : ≤37 (40 cases), C₂ : 38≤ ≤48 (37 cases), C₃ : 49≤ (7 cases). Nine autopsy infantile cases and 5 cases of resected livers were studied as control groups. (reported in Ist report.) Nuclear DNA measurement of liver cells revealed more Nuclear DNA content in C₁ group, nearly some content in C₂ group as the control. group and lesser DNA content in C₃ group. And the histochemical studies (Alkaline phosphatase, Leucin amonopeptidase, r-glutanyl transpeptidase, ) on 10 resected livers were done.