Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
Volume 27, Issue 4
Displaying 1-16 of 16 articles from this issue
Contents
  • -Part II The Nuclear DNA Measurements of Liver Cells and the Histochemical Studies-
    YASUNORI KOJIA
    1981 Volume 27 Issue 4 Pages 426-433
    Published: December 10, 1981
    Released on J-STAGE: November 21, 2014
    JOURNAL FREE ACCESS
    The histopathological studies on 84 resected livers taken at radical operations of congenital biliary atresia concluded that conditions of liver cell were devided into 3 groups (Cn classification) according to nuclei number of liver cells in (130μ) 2; i.e. C1 : ≤37 (40 cases), C2 : 38≤ ≤48 (37 cases), C3 : 49≤ (7 cases). Nine autopsy infantile cases and 5 cases of resected livers were studied as control groups. (reported in Ist report.) Nuclear DNA measurement of liver cells revealed more Nuclear DNA content in C1 group, nearly some content in C2 group as the control. group and lesser DNA content in C3 group. And the histochemical studies (Alkaline phosphatase, Leucin amonopeptidase, r-glutanyl transpeptidase, ) on 10 resected livers were done.
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  • Part 1. A Histometrical Study on Autopsy Cases of Liver Cirrhosis, Hepatomas and Gastric Cancers.
    YOSHIHARU ODANI
    1981 Volume 27 Issue 4 Pages 434-451
    Published: December 10, 1981
    Released on J-STAGE: November 21, 2014
    JOURNAL FREE ACCESS
    Metabolic disorders in the spongiosa of vertebral bones are induced chiefly by abnormalities in the calcium metabolism, and also by many other neoplastic and/or non-neoplastic chronic disorders in digestive and in lower respiratory organs which are accompanied with generalized chronic nutritional disturbances. In the present study, morphological and histometrical changes are discussed by means of histological tracing of the horizontal cut surfaces of the human 3rd lumbar vertebrae in autopsy cases of 35 liver cirrhosis, 37 hepatomas, 96 gastric cancers and in 174 variable control cases. Control cases are devided in 72 non-neoplastic disease, 64 miscellaneous cancers and 38 pulmonary cancers. In histometrical study, volume percent of trabecular bone spicules are measured by a section paper method and/or a quantitative picture analysing system (πMC : Olympus Co., Ltd.). Types of trabecular patterns of the spongiosa spicules are classified in 5 groups ; A (very marked), B1 (slight), B2 (slight), B3 (rare) and C (lack). Results : Marked reduction in volume percent of trabecular bone spicules of the spongiosa are found in each disease group. Morphological groupings of types of the trabecular patterns correspond very well numerical weight of the volume percent and fall in successive structure of trabecular bone spicules are marked in liver cirrhosis, hepatomas and gastric cancers as compared with 3 control groups. Conclusion : A histological and histometrical study on the trabecular bone spicules of lumbar vertebral spongiosa in autopsy cases of liver cirrhosis, hepatomas and gastric cancers showed marked reduction in the volume percent and difference of their morphological patterns, respectively.
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  • HARUHISA HORIKAWA
    1981 Volume 27 Issue 4 Pages 452-464
    Published: December 10, 1981
    Released on J-STAGE: November 21, 2014
    JOURNAL FREE ACCESS
    There has been a tremendous improvement on the neonatal cares, nevertheless cerebral complications are still left behind the progress. The author have had some opportunity to study autopsy cases in the medical facilities which has been leaders in the field of neonatal medical care in Japan. In this paper the author studied morphologically 50 fetal and neonatal autopsy cases obtained in the Juntendo Medical College in recent 5 years, also reviewed 750 autopsy cases in the Tokyo Mothers and Children Health Facility and Tsukiji Lying Hospital in the period of 1955 to 1977. Methods ; 1) Stereoscopic observation of the vascular system by a modified Pickworth's method. 2) Determination of the water volume of the cerebral white matters. 3) Macrostaining of the cranium to demonstrate the state of cranial bone developments by a alizalin red-alcianblue method. Conclusion ; 1. The primary site of the hemorrhages are in the boundary zone of the brain artery based on the cerebral vascular flow of premature infants. The premature infants revealed lager volumes of water in the tissue. The water volumes are larger in the intraventricular hemorrhage group than in the non-hemorrhage group in every body weights classes. The water volume is also larger in the intravenous infusion therapy group. The auther conclude that the rupture of specifically localiped veins cause a blocking effect for venous flow by way of mechanical pressure at the level of fornix near the intervetricular foramen. In the subependymal area an anoxic damage due to hypoxia can cause intraventricular hemorrhage in association with venous blocking effect by the edematous fornix. The clinical facts that the diseas appears frequently in premature infants and increase in the intravenous infusion therapy group, those are elucidated thus morphologilly. 2. Periventricular leucomalacia, which is particulary noted recently, can be understood as a disease in the boundary zone of the superficial artery or the ventricular artery of brain.3. On the ponto-subicular neuronal necrosis, which is emphasized as a manifestation of the anoxia by Friede is demonstrated (provede) as a pathological picture caused by the compression of brain tissues by the vessels in cerebellar tentorial edge, it will be influenced rather by the birth traumatic and mechanical factors. 4. Occipital osteodiastasis has been rather frequently overlooked, but in the cranium of premature infants before 30 weeks of gestation, a zone of cartilage remains between the basis and squma of occipital bone, and thus diastasis is easily to explain.
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