Abstract
Hematological reference intervals were established by using COULTER STKS (automatic blood cell counter and cell analyzer based on flow ststem). For establishment of reference intervals, 529 healthy samples were sobtaired from 336 males and 193 females between 18 and 67 years. Sex depengent differences in the reference intervals of WBC were calculated. No sex difference was observed in the reference intervals of PLT, Pct, MPV and PDW. In the statistical treatment adjustment by the XP-Type variable transformation was often necessary to obtain the normal distribution. The reference intervals for PDW were generated by the non-parametric (percentile) method instead of the parametric method because of the strong deviation in the distribution pattern. Some differences were observed between these reference values and the previous ones. The differences supposedly depend on the reference individuals and method of laboratory tests and/or amount of data. The findings suggest the adequency of resetting the reference intervals. Automated hematology analyzers provide some indexes of platelet measurements such as mean platelet volume (MPV) and platelet distribution width (PDW). MPV distribution is increased in association with the decrease in platelets (PLT). These new variables may be useful in the initial classification of platelet disorders and other disease.
