骨缺損部の「ギプス」充填に関する実験的研究 (追試)

抄録

Prof. L.E. Peltier reported a useful application of plaster of Paris to fill defects in bone. We are much interested in this common material. But, thinking to need our own experiment before the clinical application, we tried the same experiment. Plaster of Paris of dental grade was mixed with water and al.owed to set in a suitable basin. Then the set mass was cut in rectangular collumms, and sterilized by dry heat in an oven. The columns were inserted into the muscles and articial bone defects of rabbits, and X-ray, histol·gical and biochemical examinations were made. The conclusion is as follows. (1) The absorption of inserted plaster of Paris was seen markedly from the 3rd week. The bone formation was visible from the 4th week and finished in the 6th or 7th week and never delayed or disturbed in comparison with the control examination. (2) Harmless clinical application will be expected, becausc the material (i) can be completely sterilized, and (ii) is free from fear that is might stimulate the tissue for a long time as a non soluble foreign body, and (iii) contains no antigenic substances.