抄録
The laboratory records of findings in tubercle bacilli detection from the patients' sputa in a tuberculosis hospital in the suburbs of Tokyo, were analysed from the statistical point of view. Period studied was about six years from August, 1954 to April, 1960.
Modified Ziehl-Gabbet's staining method and fluoro-microscopic method were used for smear examination, and for cultivation, preoperated by 8% NaOH, samples were incubated in 3% KH2PO4 Ogawa's media. Main findings were as follows :
(1) Culture method was superior to smear method for the detection of tubercle bacilli, especially in the case of negative samples from smear method.
(2) Number of Gaffky's scale, duration until the colony of bacillus was visible, number of colonies at each time of observation and type of colonies were related each other in directly or reversely.
(3) Cultivation of negative samples from smear method showed some interesting results. Distribution of number of colonies at 13 weeks after incubation was almost logarithmic normal. Deviation was quite large compared with that of normal distribution but the number of bacillus that was able to form colonies was estimated as extremely small.
(4) Statistical analysis of the growth curves of colonies of the above samples, indicated that there was no relation between the final number of colonies and the growth curve, and that the rate of growth was highest at the initial stage after incubation, followed by the rapid decrease by week in geometric progression.
(5) Some findings were mentioned on the resistance to one. two or three drugs at several concentraion rates.
